T2Bacteria Panel

A rapid detection panel for bacterial sepsis requiring no blood culture

T2 Biosystems is committed to innovation in sepsis detection, and is currently developing the T2Bacteria Panel. Run on the T2Dx Instrument, it is designed to detect the bacterial pathogens associated with sepsis that often are not effectively treated by first-line antibiotics. The T2Bacteria Panel may enable physicians to make informed treatment decisions more quickly than ever before and to rapidly administer targeted therapy to patients.

The T2Bacteria Panel is designed to provide:

  • Test results without the need for blood culture
  • Limits of detection as low as 1 CFU/mL
  • Rapid and specific results in an average of 4.3 hours
  • Accurate results even in the presence of antimicrobial therapy

Sepsis causing bacteremia

Bacterial sepsis is a serious problem in healthcare. Of the nearly 15 million patients1 tested for blood stream infections in the United States annually, approximately 8.75 million2 are at high risk for a bacterial infection. Delays in diagnosis and treatment are negatively impacting patient health and hospital costs.3 Additionally, empiric treatment is increasing antibiotic resistance, leading to potentially deadly treatment failures.

T2Bacteria Panel for rapid diagnosis

The T2Bacteria Panel is designed to identify the species-specific source of bacterial infection in an average of 4.3 hours, which may enable physicians to implement more timely targeted antibiotic therapy. Used in conjunction with the T2Candida Panel, the T2Bacteria Panel is designed to have a revolutionary and immediate impact on the diagnosis and treatment of sepsis.

Timeline

T2 Biosystems is targeting completing the T2Bacteria Panel trial and filing with the FDA in mid-2017. 

The T2Dx Instrument and T2Candida Panel have received marketing authorization from the U.S. Food and Drug Administration. All other T2 Biosystems products are considered investigational and for research use only.

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1. T2 Biosystems Data on File
2. T2 Biosystems Data on File
3. Beekmann, S. E., Diekema, D. J., Chapin, K. C., & Doern, G. V. (2003). Effects of rapid detection of bloodstream infections on length of hospitalization and hospital charges. Journal of clinical microbiology, 41(7), 3119-3125.