Identify sepsis causing pathogens in less than 5 hours while blood cultures incubate

Imagine species identification for some of the most common and deadly sepsis-causing pathogens— without having to wait 1 to 5 days or more for blood culture results. 

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19th-Century diagnostic methods make it too easy for “ESKAPE” pathogens to escape

In 2004, microbiologist Carl Nathan, M.D., wrote in a Nature commentary that:

"Treating infections with pathogen-specific rather than broad-spectrum antibiotics (whenever possible) will require prior, rapid, accurate and specific diagnosis. It makes no sense to use 21st-century technology to develop drugs targeted at specific infections whose diagnosis is delayed by 19th-century methods."1

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3 Lessons for Sepsis Committees with Dr. Sandy Estrada

The following is edited from a conversation with Sandy Estrada, Pharm.D., BCPS, Vice President, Medical Affairs, T2 Biosystems. Dr. Estrada was previously an Infectious Diseases Clinical Pharmacist for Lee Health in Ft. Myers, FL for 13 years where she served as the Co-Director of Antimicrobial Stewardship, Director of the ID Pharmacy Residency Program, and as a member of the sepsis committee.

Sepsis Committees Get It Right With Direct Patient Care Staff Involvement:

Sepsis committees often make a priority of identifying or hiring a sepsis coordinator. This position is typically held by a nurse or emergency department clinician. This leadership role for frontline caregivers helps center the committee’s actions on a passion for patient care and a desire to seek breakthroughs that can reduce sepsis mortality and improve patient outcomes.  

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