Positive Clinical Impact of T2Candida Panel at Henry Ford Health System

Leading Infectious Disease Doctor at Henry Ford Reviews Implementation and Results of Rapid Detection of Sepsis Pathogens

Dr. George Alangaden, Senior Staff Physician Director, Transplant Infectious Diseases, Medical Director of Infection Prevention, Henry Ford Hospital System (HFHS), focuses on the following areas:

  1. Rationale for the adoption of T2 Magnetic Resonance (T2MR) at HFHS
  2. Implementation process of T2MR at HFHS
  3. Impact of the T2MR technology on the hospital and patients

Dr. Alangaden discussed some key findings on the impact of T2MR, including:

  • 4-day reduction in the length of stay in the hospital per patient;
  • 7-day reduction in the length of stay in the ICU per patient; and
  • 75% of patients with a negative T2MR result  had antifungals stopped or deescalated.

“Our early experience of the implementation of T2MR and the T2Candida Panel at Henry Ford Health System appears very promising,” said Dr. Alangaden. “T2MR implementation was associated with significant reduction in time to detection of candidemia and it improved significantly time to initiation of antifungal therapy. Unnecessary antifungals were rapidly discontinued in almost three quarters of the patients. The implementation of T2MR also resulted in reduced ICU length of stay.”

In addition to the presentation, the May 2017 webinar also included a Q&A section with Dr. Alangaden, as well as Dr. Linoj Samuel, Division Head, Clinical Microbiology, and Rachel Kenney, PharmD, Pharmacy Specialist of Antimicrobial Stewardship, both from HFHS as well. During the Q&A, they discussed the potential cost savings from the discontinued or reduced use of antifungal therapy alone, educational efforts to create understanding and proper use, initial challenges of implementation in the laboratory and steps taken to address those challenges.