Huntsville Hospital Stewardship Experience with T2Direct Diagnostics

Jonathan D. Edwards, Pharm.D., BCPS (AQ-ID), BCGP, Huntsville Hospital, discusses the economic and clinical benefits of T2Direct Diagnostics

In the Science and Industry Showcase, “Managing Sepsis in the Golden Hour: Controlling Costs and Improving Patient Care through Diagnostic Testing,” Jonathan D. Edwards, Pharm.D., BCPS (AQ-ID), BCGP, Huntsville Hospital, discussed the economic and clinical benefits of T2Direct Diagnostics direct-from-whole blood tests at Huntsville Hospital.

“With T2Direct Diagnostics, our hospital is not only reducing the use of antifungal therapy, we’re also identifying far more infected patients than was possible with blood culture,” said Dr. Edwards.

Dr. Edwards reported the following findings from Huntsville Hospital:

  • T2Candida detects more Candida infections, days faster than blood culture.
  • T2Candida provides superior sensitivity as compared to blood culture (94.4% vs. 28% sensitivity). Blood culture missed 26 confirmed Candida infections.
  • Negative T2Candida results led to cessation or no initiation of antifungal therapy in 64% of patients.
  • T2Candida improves hospital economics through de-escalation/non-initiation of unnecessary antifungals. T2Candida negative results decreased duration of micafungin by 2.1 days.