T2Bacteria Panel

Species identification in hours instead of days, including deadly ESKAPE pathogens

The T2Bacteria® Panel is the first and only FDA-cleared and CE-marked test to identify sepsis-causing bacteria directly from whole blood without the wait for blood culture.

T2Bacteria identifies:

  • 50% of all bacterial bloodstream infections1
  • 70% of all blood culture species in the emergency department2
  • 92% of deadly ESKAPE pathogens3

Species identification in just hours: The commercially available T2Bacteria Panel provides species identification in 3 to 5 hours while the current standard of care takes 1 to 5 days or more.1 One T2Bacteria test result detects the equivalent of three sets of blood cultures for many species.2

Improved time to targeted therapy: By incorporating the Panel as part of the sepsis bundle, physicians can get more patients on the right therapy faster, thus improving empiric therapy protocols, potentially preventing the progression of sepsis, while increasing the chances of both patient survival and recovery.

Game-changing performance: In the T2Bacteria pivotal clinical trial1 conducted in 11 U.S. centers with 1,427 patients, investigators demonstrated:

  • Highly accurate results – identifying 3 times more infections than the paired blood culture draw
  • Positive and negative results more than 2 days faster than blood culture
  • Opportunities to de-escalate therapy and improve time to targeted therapy by days
  • No detection interference when patients are on antibiotic therapy, a well-known limitation of blood culture

Improved stewardship: The Panel can detect all of the organisms identified by blood culture and provide significant de-escalation opportunities due to a negative S. aureus or negative P. aeruginosa result. Read Lee Health System’s experience with T2Bacteria.

Improved empiric therapy in the emergency department: A study conducted at Gemelli Hospital in Rome, Italy, reported that T2Bacteria delivered positive results more than 4.5 times faster with excellent accuracy. In a Case Study by Dr. De Angelis and colleagues presented at ECCMID, a rapid T2 result picked up a polymicrobial infection in 4 hours vs. 41 hours by traditional blood culture based method, concluding that “the T2Bacteria Panel detects infections and poly-microbial infections faster than blood culture”.

 

Contact us to request a demo of the T2Bacteria Panel!

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1. Nguyen MH, et al. Annals of Internal Medicine 2019
2. Voigt, C, et al. Manuscript under review, 2019
3. Karlowsky, JA, et al. Annals of Clinical Microbiology and Antimicrobials, 2004
4.  De Angelis G, et al, Journal of Antimicrobial Chemotherapy, 2018.
* A combination of samples was run in both the prospective and contrived arms of the study. T2Bacteria showed an overall average sensitivity of 90% in the prospective arm of the study, with an overall average PPA of 97% in the contrived arm of the study.