Hospital laboratories face ever-increasing pressure for cost control as well as demands from clinicians for faster diagnostic results. Until now, laboratories have had to rely on methods that were introduced almost 100 years ago to determine the presence and identification of bacterial and fungal infections.
New direct-from-whole blood T2Direct Diagnostics™ have been proven to complement traditional blood culture methods by identifying the most common and deadly organisms resistant to empiric therapy. With T2Direct Diagnostics tools, laboratories can now provide species-specific results in 3 to 5 hours instead of 1 to 5 or more days. The benefits include more rapid targeted treatments for patients,* a potential to de-escalate drug use, and length of stay.
Designed with the laboratory in mind, the T2Dx® Instrument fits within the most space-constrained environment. The fully automated, walkaway T2Dx is a clinical multiplex benchtop diagnostic system capable of running tests directly from 3-4 mL of whole blood. The T2Dx is:
Industry resources: For more information on T2Direct Diagnostics, see the latest publications, posters, and white papers. Learn how about T2 Biosystems’ T2MR® technology works or read in the Medical Laboratory Observer’s cover story and the Healio Infectious Disease News story.
* Henry Ford Health System demonstrated patients tested with the T2Candida Panel were treated in a median of 5 hours – more than an eightfold improvement compared to blood culture.3 Similarly, Lee Health found the time to initiation of appropriate antifungal therapy was only 6 hours from the time of blood draw in the T2Candida-positive patients.4
‡ T2Direct Diagnostics tools can help de-escalate therapy, leading to pharmacy savings and reduced nephrotoxic side effects on patients. Hospitals, including Lee Health, Huntsville Hospital, and University of Pittsburgh Medical Center have reported antifungal savings that more than covered the full cost of testing at their institutions, with as much as a 2.1 day reduction of micafungin therapy per patient.4,5,6
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1. Mylonakis E, et al. Clinical Infectious Diseases, 2015
2. Nguyen MH, et al. Annals of Internal Medicine 2019
3. Wilson NM, et al. Journal of Antimicrobial Stewardship, 2017
4. Patch ME, et al. Journal of Antimicrobial Chemotherapy, 2018
5. Edwards JD. Poster Presentation, ASM Microbe, 2017
6. Shields R, et al. Poster Presentation, IDWeek, 2018
FDA-cleared, direct-from-blood diagnostic tools:
Over 200 studies published in peer-reviewed journals have featured T2MR in a breadth of applications
T2 Biosystems, an emerging leader in the field of in vitro diagnostics, is dedicated to saving lives and reducing the cost of healthcare by empowering clinicians to effectively treat patients faster than ever before. T2 Biosystems is focused on addressing critical unmet needs in healthcare starting with sepsis, one of the deadliest and most expensive conditions in hospitals today.
The T2Dx Instrument, the T2Bacteria and T2Candida Panels have received marketing authorization from the U.S. Food and Drug Administration. All other T2 Biosystems products are considered investigational and for research use only.
T2 Biosystems®, T2MR®, T2Bacteria®, T2Candida®, T2Resistance® and T2Dx® are registered trademarks of T2 Biosystems, Inc. “T2Biosystems” and the T2 Biosystems, Inc. logo design are registered trademarks or trademarks of T2Biosystems, Inc. All software and documentation is subject to T2 Biosystems, Inc. copyrights. All rights reserved. T2Direct Diagnostics™, T2HemoStat™, T2Plex™, T2Cauris™, T2Lyme™ and T2SARS-CoV-2™ are trademarks of T2 Biosystems, Inc.
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