Close this search box.
Close this search box.

Secondary Candidemia in Critically Ill COVID-19 Patient

T2Candida enabled the detection of candidemia 29 hours before a positive blood culture was returned. Early detection allowed for the rapid initiation of antifungal therapy in a critically ill COVID-19 patient.

Lee Health | Fort Myers, Florida

Patient History

Age and Sex: Elderly Male
History: Patient was admitted to the hospital with confirmed COVID-19. His past medical history included Type 2 diabetes mellitus and hypertension
Presentation: The patient required oxygen support via nasal cannula. A chest radiograph showed bibasilar infiltrates and initial blood cultures were negative.
Risk Factors: The patient had multiple risk factors for candidemia during hospitalization.

  • Presence in ICU
  • Broad-spectrum antimicrobial therapy
  • Immunosupressing medications

Evaluation and Treatment

Day 1
The patient was initiated on azithromycin and methylprednisolone, was given one dose of convalescent plasma

Day 2
Patient was administered 1 dose of tocilizumab (8mg/kg)

Day 3
Patient was intubated for worsening respiratory status

Day 14
Patient developed new fever, chest x-ray showed increased opacities, broad-spectrum antimicrobial therapy was initiated for suspected bacterial pneumonia

Day 15 & 16
Fever escalates (Tmax 101.9F and 103F, respectively). Additional blood cultures were obtained and T2Candida was ordered. T2Candida was positive for Candida albicans/Candida tropicalis 29 hours before the positive blood culture. On the evening of day 16 anidulafungin was initiated

Day 18
Patient defervesced

Day 30
Patient was discharged to a long-term acute care center


  1. Cubillos, A., et al. CAP, 2021
According to the CDC, of the 154 million prescriptions for antibiotics written in doctors’ offices and emergency departments each year, 30% are unnecessary.12


Over 200 studies published in peer-reviewed journals have featured T2MR in a breadth of applications.