In both of these clinical case studies, T2Bacteria® identified the causative pathogen days sooner than blood culture and allowed for the earlier initiation of targeted therapy.1
Butler Health System | Butler, PA
Case 1
Age and Sex: 70-year-old male
Presentation: The patient presented with shortness of breath, hypothermia, hypertension and was admitted. The patient had no sepsis indicators and no action was taken for sepsis screening.
Vitals: T = 99.8; BP = 152/86; P = 70
Evaluation and Treatment
Day 0
• WBC = 23.2, MDW* = 23.05 lactic acid = 1.0,PCT = .32
• T2Bacteria Result: The T2Bacteria Panel was positive for Enterococcus faecium, and the patient was initiated on targeted therapy
Day 1
• Blood culture confirmed Enterococcus faecium.
T2Bacteria allowed for targeted therapy 20 hours faster than blood culture alone.
Case 2
Age and Sex: 67-year-old male
Presentation: The patient presented with altered mental status and hypotension, and was admitted. The patient had no sepsis indicators and no action was taken for sepsis screening.
Vitals: T not taken, BP= 62/44, P = 53
Evaluation and Treatment
Day 0
• WBC = 24.7, MDW* = 23.98, lactic acid = 1.0, PCT = 4.25
Day 1
• T2Bacteria Result: The T2Bacteria Panel was positive for Pseudomonas aeruginosa, and the patient was initiated on targeted therapy
Day 3
• Blood culture confirmed Pseudomonas aeruginosa.
T2Bacteria allowed for targeted therapy 37 hours faster than blood culture alone.
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*This institution uses an algorithm combining Monocyte Distribution Width (MDW) from Beckman Coulter and white blood count (WBC) metrics as an indicator to run T2Bacteria.
- Patterson, R., Katsaros, S., Industry Showcase, ASM 2023